From agon; to struggle, literally (to compete for a prize), figuratively (to contend with an adversary), or genitive case (to endeavor to accomplish something) -- fight, labor fervently, strive.
see GREEK agon
1. to enter a contest; contend in the gymnastic games: 1 Corinthians 9:25.
2. universally, to contend with adversaries, fight: followed by ἵνα μή, John 18:36.
3. figuratively to contend, struggle, with difficulties and dangers antagonistic to the gospel: Colossians 1:29; 1 Timothy 4:10 (L T Tr text WH text; for Rec. ὀνειδιζόμεθα); ἀγωνίζομαι ἀγῶνα (often used by the Greeks also, especially the Attic), 1 Timothy 6:12; 2 Timothy 4:7.
4. to endeavor with strenuous zeal, strife, to obtain something; followed by an infinitive, Luke 13:24; ὑπέρ τίνος ἐν ταῖς προσευχαῖς, ἵνα, Colossians 4:12. (Compare: ἀνταγωνίζομαι, ἐπαγωνίζομαι, καταγωνίζομαι, συναγωνίζομαι.)